Effect of an analgo-sedation protocol for neurointensive patients: a two-phase pilot study
Not Applicable
Completed
- Conditions
- Nervous System DiseasesSedation and pain management in mechanically ventilated neurointensive care patients
- Registration Number
- ISRCTN80999859
- Lead Sponsor
- Copenhagen University Hospital (Denmark)
- Brief Summary
2010 results in https://pubmed.ncbi.nlm.nih.gov/20403186/ (added 29/12/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 215
Inclusion Criteria
1. Both males and females, >17 years old
2. Admitted to the neurointensive care unit (NICU)
3. Tracheally intubated within 24 hours
4. Mechanically ventilated
5. Receiving continuous infusions of sedatives and analgesics
Exclusion Criteria
1. Potential organ donors
2. Non-sedated and non-intubated patients
3. Patients transferred intubated from other units
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. A shift from sedation-based to analgesia-based sedation (analgo-sedation), assessed from the chages in the use of sedatives and analgesic agents in each patient<br> 2. Improved pain management, assessed daily in each patient using the Pain Intensity (PI) scale<br><br> For all primary and secondary outcome measures, the participants were followed-up until they were off mechanical ventilation and sedation.<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Incidence of late pneumonia. Late pneumonia was defined as pneumonia acquired >48 hours after intubation.<br> 2. Accidental extubations<br> 3. Duration of sedation<br><br> For all primary and secondary outcome measures, the participants were followed-up until they were off mechanical ventilation and sedation.<br>