Prediction of Donor Liver Adipose Content by Magnetic Resonance Imaging
Not Applicable
Withdrawn
- Conditions
- Steatosis of LiverFatty Liver
- Interventions
- Other: MRI of donor liver prior to transplant
- Registration Number
- NCT02873507
- Lead Sponsor
- Vanderbilt University Medical Center
- Brief Summary
A pilot prospective cohort study assessing the clinical utility of MRI evaluation of graft steatosis prior to transplantation will be conducted. An MRI of the donor liver within the transport cooler will be obtained on its way to the operating room.
- Detailed Description
The images from MRI will be analyzed to obtain information of fat content in all eight segments of the liver. Demographic, intra-operative, and post-operative patient data will be collected for each imaged graft.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Patients who are scheduled to orthoptic liver transplant
Exclusion Criteria
- Patient's who do not agree to sign consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description MRI of donor liver MRI of donor liver prior to transplant MRI evaluation of graft steatosis in donor liver prior to transplantation
- Primary Outcome Measures
Name Time Method Percent Hepatic Steatosis of a Donor Liver Prior to Transplantation Measured immediately prior to liver transplant Amount of fat measured in the donor liver prior to transplant surgery using MRI scan
- Secondary Outcome Measures
Name Time Method Comparison of steatosis percentages provided by biopsy to MRI results Baseline Length of hospitalization of transplant recipient Days to hospital discharge, approximately 2 weeks Mortality of liver transplant recipient at 1 year post transplantation 1 year