Characterization of endothelial function, arterial stiffness and inflammation in Atrial Fibrillation: Effect of cardioversio

Not Applicable

Withdrawn

• Conditions: Atrial fibrillation; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12614000642684
• Lead Sponsor: Centre for Heart Rhythm Disorders University of Adelaide

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-06-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

This study will consist of evaluating patients who are undergoing a therapy directed at restoring sinus rhythm, ie. electrical cardioversion; patients of both sexes aged > 18 yrs meeting the following criteria will be enrolled. Consecutive patients with AF undergoing elective cardioversion at the Royal Adelaide Hospital or Wakefield Hospital will be eligible for this study. Endothelial function testing will be performed pre and 2 hours post procedure.

Exclusion Criteria

Patients will be excluded if they have known causes of acute AF (such as pneumonia or other infections, alcohol excess, pulmonary embolism), significant heart valve disease, acute cardiovascular or cerebrovascular events (myocardial infarction, acute coronary syndrome or stroke) within the last 3 months, malignancy, connective tissue disease, chronic infection, inflammatory conditions, renal or hepatic dysfunction. We will exclude patients who, for any reason, are contra-indicated to undergo cardioversion of AF. As a final exclusion, patients unable to undergo a brief general anaesthetic will not be enrolled.

Study & Design

• Study Type: Interventional
• Study Design: Not specified