CTRI/2022/03/040802
Active, not recruiting
Phase 2
PROphylaxis for paTiEnts at risk of COVID-19 infecTion - PROTECT
The George Institute New Delhi0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
- Sponsor
- The George Institute New Delhi
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Inability to provide informed consent or to comply with trial procedures
- •2\) COVID\-19 at time of enrolment – either positive SARS CoV\-2 swab (PCR) or symptoms highly suggestive of COVID\-19 infection
- •3\) Known chronic liver disease or hepatic dysfunction as evidenced by ALT or AST \> 3x upper limit of the normal range
- •4\) Allergy to niclosamide or history of significant adverse reaction to niclosamide or related compounds, or to any of the excipients used
- •5\) Significant structural nasal disease in the opinion of the investigator
- •6\) Pregnant, trying to conceive, unwilling to use contraception or breastfeeding
- •7\) Participation in another interventional prophylactic or vaccine trial against COVID\-19
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Phase 1
PROphylaxis for paTiEnts at risk of COVID-19 infecTion - PROTECTEUCTR2020-004144-28-GBCambridge university Hosptials NHS Foundation Trust and University of Cambridge1,500
Active, not recruiting
Phase 2
Preventative treatment for patients at risk of COVID-19 infection (PROTECT)COVID-19 (SARS-CoV-2 infection) in dialysis, vasculitis, and kidney transplant patientsInfections and InfestationsISRCTN88057279Cambridge University Hospitals NHS Foundation Trust5,000
Completed
Not Applicable
International ALLIANCE Study of Therapies to prevent progression of COVID-19, a randomized trialCOVID-19Infection - Other infectious diseasesRespiratory - Other respiratory disorders / diseasesACTRN12620000557932AProf Dr Karin Ried446
Recruiting
Phase 1
Therapies to prevent progression of COVID-19 in outpatients: The 'Primary Care Australian COVID-19 Therapeutics' (PACT) TrialACTRN12622000386730AProf Dr Karin Ried300
Withdrawn
Not Applicable
International ALLIANCE Study of Therapies to prevent progression of COVID-19, a randomized trial - Stage 2COVID-19Infection - Other infectious diseasesRespiratory - Other respiratory disorders / diseasesACTRN12622000309785AProf Dr Karin Ried200