Comparing the Baerveldt and Paul glaucoma drainage devices and their effects on the corneal endothelium

• Conditions: glaucoma; 10018307

• Registration Number: NL-OMON51284
• Lead Sponsor: Oogziekenhuis Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 160

Inclusion Criteria

Age 18 - 75 years.
Caucasian ethnicity (to facilitate comparison of results with those of earlier
work).
Primary open-angle glaucoma, pseudoexfoliative glaucoma, or pigmentary
glaucoma.

Exclusion Criteria

Normal pressure glaucoma.
History of ocular surgery (e.g. intraocular or strabismus surgery, tenon*s
capsule or conjunctiva surgery, cyclodestructive procedures etc).
History of ocular comorbidity (e.g. active uveitis, proliferative diabetic
retinopathy).
Pseudophakia.
Functionally monocular patients.
Need for glaucoma surgery combined with other ocular procedures (i.e. cataract
surgery, keratoplasty, or retinal surgery) or an anticipated need for
additional ocular surgery.
Narrow anterior chamber angle.
Best corrected visual acuity less than 0.1.
Severe blepharitis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Endothelial cell density and tube position at 24 months.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Intraocular pressure<br /><br>Motility<br /><br>Flare</p><br>