Development of molecular diagnostic markers using oral fluid for diagnosis of periodontitis in diabetes : a pilot study

Asan Medical Center0 个研究点目标入组 24 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

暂无简介。

•A. Periodontal Disease
•- Patients with chronic periodontitis
•- Patients required primary treatment of periodontal scaling, subgingival curettage, and agreed agreed with the basic periodontal therap based on the standard protocol
•- subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing
•B. Diabetics
•Satisfy one of the following three
•1) The typical symptoms of diabetes ( polyuria, erudite , dagal , unexplained weight loss) while blood glucose levels are 200 mg / dL or higher
•2) fasting plasma glucose concentration was 126 mg / dL or higher
•3) glucose tolerance test glucose levels 2 hours after the load (PP2, 2 hrs post-prandial plasma glucose level) is more than 200mg/dL
•- subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing
•- Healthy periodontal patients ( more than 20 permanent teeth are present , in all parts of deep periodontal pockets measuring 4mm or less, and height is 2mm or less clinical attachment person)
•- subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing

•- Received periodontal treatment within the last six months
•- recently taken antibiotics within 3 months if you need a prescription antibiotic prophylaxis
•- taking the drug can affect periodontal status for a long period of time
•- pregnant or breastfeeding
•- In case of oral inflammatory mucosal disease (Lichen planus, etc.)
•- Patients with a history of alcoholism or drug abuse
•- other special systemic disease (high blood pressure)
•- ages under 18

发起方