Proton therapy of brain tumors: Prospective collection of effectiveness and side effects with standard clinical doses

Not Applicable

Recruiting

• Conditions: C71; D32; D33; Malignant neoplasm of brain; Benign neoplasm of meninges; Benign neoplasm of brain and other parts of central nervous system

• Registration Number: DRKS00007670
• Lead Sponsor: niversitätsklinikum DresdenKlinik für Strahlentherapie und Radioonkologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-02-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

brain tumor: gliomas (low or high grade), meningiomas, pituitary adenoma, craniopharyngiomas and other rare brain tumors and AV malformations
- Age >= 18 years old
- ECOG > 2
- Indication for high-dose radiotherapy or radiochemotherapy
- Capacity to consent and written consent of the patient

Exclusion Criteria

- Lack of capacity to consent or lack of written consent of the patient
- Inability to MRI planning (eg. contraindications to performing MRI)
- Lack of compliance of the patient
- Lack of or limited possibility of a reproducible storage (eg by severe restriction of mobility of the patient)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
>= grade late II toxicity after 2 years, evaluation by Kaplan-Meier plots

Secondary Outcome Measures

Name	Time	Method
local tumor control and acute toxicity > stage II after 2 years, evaluation by Kaplan-Meier plots