Exploratory research into the effect of temporarily withdrawal of PPIs (Proton Pump Inhibitor) use, to reduce the stomach wall uptake of 99mTc-Sestamibi in a myocardial perfusion imaging
- Conditions
- cardiac researchmyocardial perfusionscintigraphy1002859310003216
- Registration Number
- NL-OMON42879
- Lead Sponsor
- Rijnstate Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 60
- Patients with a cardiology reference indication for myocardial perfusion imaging.
- Patients older than 18 years.
- Patients wherein for the myocardial perfusion preformed with etheir adenosine or regadenoson
- Patients taking preventive less than 90 days using PPIs
- Patients who have signed an informed consent.
- Patients in which the scan was performed on the scanner BrightView 1 in Nucleare department Rijnstate Arnhem.
- Patients who have no defects at the myocardal inferiorwall.
- Patients with dyspepsia
- Patients with only uptake in the stomach cavity, thus no reliable measurement can be done and no visually assesment can be reliable preformed.
- Patients who are not prepared and tested according to the protocols
- Patients with the following well-known diseases, Zollinger Ellison Syndrome, a barrettoesofagus or a esophagitis with endoscopic grade C or D
- Patients partially been injectjet or underskin injection, no maximum uptake of radiopharmaceutical is can be reached.
- Patients that use medications that interact with PPIs.
- Patients with gastric resection or surgically treated for stomach problems.
- Patients with gastric ulcer prophylaxis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method