Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Change in Body Temperature in Children Undergoing MRI Under General Anesthesia (GA)and Change in Room Temperature Before and After MRI
研究概览
简要总结
The number of children undergoing MRI imaging has increased significantly in the past years, because many young children cannot stay still for the duration of the scan, have difficulty tolerating the confined space and the noise produced by the Magnetic Resonance Imaging (MRI) machine, sedation or General Anesthesia is required in these cases. In the investigators institution, the investigators use General Anesthesia for children undergoing MRI.
Because children have a larger surface area to body weight ratio; hypothermia from passive heat loss is one of the anesthesiologists' concerns.
MRI requires a cool environment with low humidity; this specialized environment represents a significant thermal challenge to the anesthetized children. Since most temperature devices are not compatible with the MRI, the simple task to measure temperature change has never been investigated.
详细描述
It is known that following the induction of anesthesia, core hypothermia occurs in three stages;
- Redistribution
- Linear phase
- Plateau phase Redistribution This accounts for the largest drop in core temperature of the three stages. Vasodilatation causes redistribution of heat from the core to the periphery.
Linear Phase This begins at the start of surgery as the patient is exposed to cold cleaning fluids and cool air flow in the theatre. Heat loss exceeds heat production, and most surgery does not extend past the linear phase.
- Radiation contributes the most (40%) and is proportional to environment/core, temperature difference to the power of four.
- Convection contributes up to 30% and is proportional to air velocity.
- Conduction contributes up to 5% and is proportional to the difference in surface temperatures.
- Evaporation contributes up to 15% and occurs from cleaning fluids, skin, respiratory and wound. A laparotomy can contribute up to 50% of the total.
- Respiratory contributes 10% (8% evaporation of water; 2% heating of air) and is enhanced by the cooling effect of cold anesthetic gases.
- Cold intravenous fluids. Plateau Phase Once core temperature falls below the thermoregulatory threshold, peripheral vasoconstriction increases and acts to limit the heat loss from the core department. When core heat production = heat loss to the peripheral compartment, core temperature reaches a plateau. Patients with an autonomic neuropathy (diabetics) have impaired sympathetic vasoconstriction and are unable to establish a core plateau in phase 3. Combined general and regional anesthesia will have a similar effect as the regional anesthetic (spinal/epidural) will prevent vasoconstriction in the legs; i.e. failure to establish a core plateau.
The ability to maintain body temperature is also compromised because anesthesia impairs intrinsic thermoregulatory response.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Months 至 8 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •6 months to 8 years undergoing general anesthesia for elective MRI of brain, spine and extremities. Patients who were ASA physical status 1-3 only were included.
- •exclusion criteria: Patients who were ASA 4-5 were excluded from the study. Patients not NPO for solids for 8 hours and liquids for 2 hours were excluded.
排除标准
- 未提供
结局指标
主要结局
Change in Body Temperature in Children Undergoing MRI Under General Anesthesia (GA)and Change in Room Temperature Before and After MRI
时间窗: prior to induction of general anesthesia and at conclusion of MRI an average of two hours
Axillary temperature was measured with MRI-compatible Tempa dot immediately before general anesthesia was induced. Second axillary temperature reading was taken at the conclusion of the MRI scan before emergence from general anesthesia. Room temperature was measured with a digital thermometer placed in scanner room outside the magnet range.
次要结局
- Relationship Between Pre MRI Body Temperature and Change in Body Temperature After MRI(Prior to start of general anesthesia and immediately after completion of MRI an average of two hours)
- Relationship Between Body Surface Area (BSA) and Change in Body Temperature After MRI(Prior to start of general anesthesia and immediately after completion of MRI scan an average of two hours)
研究者
Anuradha Patel
Associate Professor, Dept. of Anesthesiology
Rutgers, The State University of New Jersey
