IRCT20191003044971N1
Recruiting
Phase 3
Evaluation of nasal oxytocin spray efficacy in scales of the withdrawal sign and craving and relapse When cutting methadone in opioids addicted people that have received methadone .
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- drug addiction.
- Sponsor
- Tehran University of Medical Sciences
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •These people are all men.
- •They are between 18 and 55 years old.
- •They have a history of drug addiction, with the drug being discontinued and replaced with methadone.
- •The amount of methadone consumed is between 10 and 100 mg
- •They have been on methadone maintenance therapy for longer than 6 months
- •now on his own offer Or, as the need arises (example with travel abroad, employment or marriage)he wants to cut off methadone consumption.
- •But despite the high tendency to Interruption of methadone has not been able to reduce methadone levels
- •in 14 days Recently, his methadone dose has not changed.
- •This pations were no positive morphine test for the past 3 months.
Exclusion Criteria
- •There is a history of seizures
- •Recent history of brain injury
- •drug abuse in the past 3 months
- •Severe suicidal thoughts with severe depression
- •Severe allergic disease
- •Severe neurological disorders, especially if it causes increased risk of seizure
- •Acute cardiac abnormalities present
- •History of psychotic disorders
- •acute vascular disorders
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 3
Evaluation of Intranasal oxytocine spray effect on preventing post-dural puncture headache after cesarean sectiopost-dural puncture headache.Spinal and epidural anesthesia-induced headache during the puerperiumO89.4IRCT20201215049725N1Karaj University of Medical Sciences170
Not yet recruiting
Phase 3
Evaluation of the effectiveness of oxytocin by placebo nasal spray on symptoms and treatment of adults with autismAutistic Disorder.Autistic disorderF84.0IRCT20200404046938N1Tehran University of Medical Sciences40
Not yet recruiting
Phase 3
The efficacy of intranasal oxytocin before applied behavior analysis (ABA) therapy with autistic spectrum disorderIRCT20211004052670N1Esfahan University of Medical Sciences70
Completed
Not Applicable
Evaluation of efficacy of intranasal oxytocin spray on children with autistic disorderAutistic disorderJPRN-UMIN000003812Osaka University United Graduate School of Child Development20
Active, not recruiting
Phase 1
Oxytocin intranasal administrations in children with Prader-Willi syndrome aged from 3 to 12 years.EUCTR2016-003273-18-FRniversity Hospital of Toulouse40