Quality of life after surgery and other options to prevent cancer of the lining of the womb (endometrial cancer)

Not Applicable

• Conditions: ynch syndrome; Cancer; Hereditary non-polyposis colorectal cancer (HNPCC)

• Registration Number: ISRCTN17432105
• Lead Sponsor: Queen Mary University of London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-12-17
• Last Update Posted: 19 February 2024
• Study Completion: 2025-01-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 750

Inclusion Criteria

1. Female
2. Age >18 years old
3. Lynch Syndrome diagnosis - confirmed germline mutation in MLH1, MSH2, MSH6, PSM2, ECPAM
4. UK Resident

Exclusion Criteria

1. Unwilling or unable to provide informed consent
2. Inability to understand written and verbal English

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Health-related utility scores for risk-reducing hysterectomy for endometrial cancer prevention, measured using EQ-5D questionnaire at baseline