The effect of reaching training with active transcranial random noise stimulation (tRNS) on arm function compared to reaching training with sham tRNS in people with chronic stroke and severe arm paresis.

Dr Kathryn Hayward0 个研究点目标入组 8 人开始时间: 2014年9月4日最近更新: 2022年11月28日

适应症

试验速览

暂无简介。

•All participants will be first time adult (greater than 18 years) stroke survivors who are 6 to 24 months post stroke who demonstrate severe upper limb paresis (as indicated by a Motor Assessment Scale item 6 score of less than 4 out of a possible 6 points). A minimum level of active movement consistent with a triceps brachii score of 2- is required, along with the ability to understand single stage commands. All participants will not have participated in any rehabilitation services for their arm for at least 2-weeks prior to commencement of training.

•Exclusion criteria include: 1) any contraindications to tRNS or MRI, 2) presence of neurological conditions other than stroke e.g., Parkinson’s disease, or upper limb comorbidities that could limit functional recovery e.g., arthritis, 3) elbow contracture greater than 15 degrees, or 4) currently taking medication/s that could alter cortical excitability (e.g., antiepileptic medications, antidepressants) or have a presumed positive or negative effect on neural plasticity (e.g., dopamine, dexamphetamine).

发起方

Dr Kathryn Hayward