Hypertensive Disorders of Pregnancy in Adolescence and Primipaternity
- Conditions
- Preeclampsia
- Registration Number
- NCT01374477
- Lead Sponsor
- Saint Thomas Hospital, Panama
- Brief Summary
Hypertensive disorders of pregnancy are one of the most frequent complications of pregnancy, being a serious health problem around the world.
Previous studies have suggested that there is an association between a short period of exposure to paternal sperm of a new sexual partner and the development of an immunological reaction that could trigger a hypertensive disorder of pregnancy. For this reason we want to study the relationship between the primipaternity concept (exposure to male antigens present in semen over a short period of time previous to the pregnancy) and the development of preeclampsia in adolescents.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 110
- 19 year old or less
- Pregnancy > 24 weeks at the moment of delivery
- 20 years old or more.
- Pregnancy < 24 weeks at the moment of delivery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence of a primipaternity factor Two months The presence of primipaternity factor. They include:
1. Sexual Cohabitation (timeframe between first sexual intercourse and pregnancy \< 4 months)without the use of a barrier contraceptive.
2. Oral sex with ejaculation (previous to pregnancy \< 4 months).
- Secondary Outcome Measures
Name Time Method Maternal complications Two months Presence of a complication related to preeclampsia: abruptio placenta, HELLP syndrome, eclampsia.
Trial Locations
- Locations (1)
Saint Thomas Hospital
🇵🇦Panama, Panama