Impact of pressure targeted modes of ventilation on diaphragmatic function as assessed using ultrasonography in critically ill patients with cerebral insult

未提供0 个研究点目标入组 60 人开始时间: 2021年12月6日最近更新: 2023年5月29日

适应症

试验速览

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•Patients age = 21 years.
•Both genders.
•Mechanically ventilated patients due to primary cerebral insult (ischemic or hemorrhagic or embolic incident) or secondary to traumatic brain injury in ER or OR.
•Eligible for proposed pressure targeted modes of mechanical ventilation.
•Hemodynamically stable patients or with minimal doses of vasopressors or inotropes.
•Minimal doses of sedation if needed.

•Refusal of the legal guardians to the intervention or participation of the patient in the study.
•Use of Neuromuscular blockers.
•Patient < 21 years old.
•Diaphragmatic dysfunction on ICU admission.
•History of Diaphragmatic palsy or Diaphragmatic hernia.
•History of brainstem injury or cervical spine injury or neuromuscular disease.
•Severe Hemodynamically unstable patients.
•Presence of ascites or colonic distention or any mechanical factor in the chest or abdomen interfering with diaphragmatic mobility.
•Presence of chest deformities or pneumothorax or pneumomediastinum or pleurodesis or moderate to severe pleural effusion or surgical emphysema in the chest.
•Rhabdomyolsis.
•Cachectic and malnourished patients.
•Pregnancy.
•Psychiatric illness.
•Patients with chronic pulmonary disease or respiratory failure.

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