Computational Fluid Dynamics Analysis of Blood Flow in Cerebral Aneurysms: Prospective Observational Study
Not Applicable
Recruiting
- Conditions
- unruptured cerebral aneurysm
- Registration Number
- JPRN-UMIN000013584
- Lead Sponsor
- ational Hospital Organization
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
Not provided
Exclusion Criteria
dissecting cerebral aneurysm bacterial cerebral aneurysm cerebral aneurysm treated with clipping surgery and/or coil embolization the case that examinations of contrast radiography are not possible due to any reason, such as contrast media allergy, renal impairment, and/or pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Distributions of hemodynamic factors, including normalized wall shear stress, wall shear stress gradient, oscillatory shear index, gradient oscillatory number, are evaluated among the ruptured aneurysm group, the enlarged aneurysm group, and the non-ruptured & non-enlarged aneurysm group.
- Secondary Outcome Measures
Name Time Method 1. In order to clarify the effect of hemodynamic factors on aneurysm growth, we virtually reconstruct arterial geometry of human cerebral aneurysms just before the development of aneurysms by artificial removal of the aneurysm, and compare values of hemodynamic factors between aneurysm-developed side and non-developed normal side. 2. Modified Rankin Scales are evaluated between the surgical group and the non-surgical group.