Influence of Variations in Systemic Blood Flow and Blood Pressure on Cerebral Oxygenation during Cardiac Surgery.
- Conditions
- Mensen aan een extra-corporeel circuitThe influence of variations in blood pressure and variations in blood flow on cerebral autoregulation
- Registration Number
- NL-OMON32638
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
-patient is older than 18 years
-patient is scheduled to undergo elective cardiac surgery with the use of an cardiopulmonary bypass.
-informed consent
Exclusion Criteria
-patient under 18 years old
-patient older than 70 years
-Carotid artery stenosis (examination before surgery with echo-Dopplergraphy)
-emergency operations
-severe COPD
-no informed consent
-SaO2 < 90% at room temperature
-diabetes
-Renal falure
-Brain pathology (CVA) in history
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The relationship between variations in blood pressure and blood flow on the one<br /><br>hand, and cerebral oxygenation on the other hand.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The effect of phenylephrin and vasopressin on cerebral oxygenation</p><br>