How does the heart and cardiovascular system adapt to training in a hot environment?
- Conditions
- Prolongation of orthostatic tolerance in patients with reflex syncopeNot Applicable
- Registration Number
- ISRCTN16534102
- Lead Sponsor
- eeds Beckett University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 22
1. Aged 18-44 years
2. Regularly compete in endurance based exercise (=3 times a week and/or =5-hours a week). Have not been heat acclimated or been exposed to hypoxic conditions within the last 3 months (i.e. trained or competed in environmental temperatures of =25°C or altitude =2500m)
3. A non-smoker, with no history of cardiovascular or respiratory problems
1. Suffered previously from heat illness (i.e. nausea, loss of consciousness or dizziness)
2. Any ankle, knee, leg, hip or back problems
3. History of cardiovascular or respiratory problems such as severe asthma.
4. Diagnosed with medical conditions such as diverticulitis, inflammatory bowel disease, gag reflex disorders or impairments.
5. Suffering from diarrhoea, haemorrhoids, bleeding tendencies, constipation, or intestinal complications.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Orthostatic tolerance using a tilt test with lower body negative pressure at Visit 1 (baseline) and Visit 14
- Secondary Outcome Measures
Name Time Method <br> 1. Performance time trial (TT) (20km completed as quickly as possible) Visits 4 (baseline) and 13<br> 2. Physiological and perceptual responses measured by a heat stress test ((45 minutes of fixed intensity (2.5W.kg-1) exercise on a cycle ergometer, under hot-humid conditions (32? & 70% RH) with measurement of heart rate, core temperature, sweat rate, perceived exertion and thermal sensation)) at visit 5(baseline) 9 and 12.<br>