Comparison of cardiovascular response to the laryngoscopy and tracheal intubation after induction of anesthesia by propofol or etomidate
- Conditions
- General anesthesia.Other complications of anaesthesia
- Registration Number
- IRCT201304166617N2
- Lead Sponsor
- Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
being aged from 18 to 45 years old; having no underlying diseases; being of ASA 1 classification; being an applicant for elective orthopedic surgery on upper and lower extremities; not being allergic to anesthetic drugs; not having any expected problems of the airway; receiving no narcotics or sedative drugs before the anesthesia and not being hemodynamic unstablility before the anesthesia. Patients who were a 4 grade after the induction of anesthesia and laryngoscopy, or their laryngoscopy were lasted longer than 30 seconds, or were not anesthetized using the mentioned dose of drugs and received higher doses, were excluded from the study.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: mm-hg, sphygmomanometer.;Diastolic bllod pressure. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: mm-hg, sphygmomanometer.;Mean arterial pressure. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: mm-hg, sphygmomanometer.;Heart rate. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: ECG monitor.;O2 saturation. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: Pulseoxymeter.
- Secondary Outcome Measures
Name Time Method Hypotension. Timepoint: Other complications of anaesthesia. Method of measurement: mm-Hg, sphygmomanometer.;Hypertension. Timepoint: Other complications of anaesthesia. Method of measurement: mm-Hg, sphygmomanometer.;Tachycardia. Timepoint: Other complications of anaesthesia. Method of measurement: ECG monitor.;Bradycardia. Timepoint: Before intervention, at laryngoscopy time and 1 , 3 ,5 , 10 min after drug injection. Method of measurement: ECG monitor.