White Box Modeling of Self-Determine Sequence Exercise Program Among Sarcopenic Elderly: Uncovers a Novel Strategy Overcoming Decline of Skeletal Muscle Area
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sarcopenia
- Sponsor
- Northeast Normal University
- Enrollment
- 392
- Locations
- 1
- Primary Endpoint
- Using a bioelectrical impedance body composition analyzer with a multifrequency device to investigate the change of relative skeletal muscle mass index in sarcopenic elderly.
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Sarcopenia is a geriatric condition characterized by a progressive decrease in skeletal muscle content and loss of muscle function. Resistance exercise, Taichi exercise and the hybrid exercise program consisting of the two aforementioned methods have been demonstrated could increase the skeletal muscle mass of the elderly with sarcopenia. However, note that the above contents may be performed in a different order in a treatment, equally important but less well understood is the sequence in which it should be performed. Surprisingly, the exercise sequence has not been comprehensively investigated. Therefore, investigators designed a self-ordered exercise program combining resistance exercise, tai chi and a hybrid exercise program to investigate whether the decline in skeletal muscle area could be better overcome and the reversal of sarcopenia in elderly with sarcopenia.
Investigators
Guang Yang, Prof. Dr.
Prof.Dr.
Northeast Normal University
Eligibility Criteria
Inclusion Criteria
- •satisfied the Asian screening criteria for sarcopenia by the Asian Working Group for Sarcopenia;
- •age higher than 60 but less than 75 years of age.
Exclusion Criteria
- •with serious illness or breathing failure;
- •with neuro-muscular diseases;
- •taking medication that has an effect on the function of skeletal muscles;
- •with conditions relating to the neurological system or the mental health;
- •in another scheduled training plan.
Outcomes
Primary Outcomes
Using a bioelectrical impedance body composition analyzer with a multifrequency device to investigate the change of relative skeletal muscle mass index in sarcopenic elderly.
Time Frame: Month 6
Participants will receive a relative skeletal muscle mass index test before and after the intervention to assess the change from baseline relative skeletal muscle index at 6 months.
Using quantitative CT to investigate the change of skeletal muscle area in sarcopenic elderly.
Time Frame: Month 6
Participants will receive quantitative CT scans before and after the intervention to assess the change from baseline skeletal muscle area at 6 months.
Using a Jamar hydraulic hand dynamometer to investigate change of handgrip in sarcopenic elderly.
Time Frame: Month 6
Participants will receive a handgrip strength test before and after the intervention to assess the change from baseline handgrip strength at 6 months.
Secondary Outcomes
- Collect participants' self-evaluation of their life state and physical state.(Month 6)
- Collect video of participants throughout the intervention.(Month 6)