Effects of Exercise on sRAGE Levels and Cardiometabolic Risk Factors

Not Applicable

Completed

• Conditions: Type 2 Diabetes
• Interventions: Behavioral: Control Group; Behavioral: Aerobic Exercise Group

• Registration Number: NCT01542775
• Lead Sponsor: Korea University

Brief Summary

The purpose of this study is to examine the effects of exercise on diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2011-12
• Status Verified: 2012-02
• Study First Submitted: 2012-02-20
• Study First Submitted QC: 2012-03-01
• Last Update Submitted: 2012-03-01
• Study First Posted: 2012-03-02
• Last Update Posted: 2012-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• type 2 diabetes
• stable body weight
• sedentary lifestyle

Exclusion Criteria

• smoked cigarettes
• cardiovascular disease
• chronic kidney
• chronic liver disease
• pregnant or breastfeeding
• any other major illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Control Group	-
Exercise	Aerobic Exercise Group	-

Primary Outcome Measures

Name	Time	Method
change from baseline in soluble receptor for advanced glycation endproducts (sRAGE) after 12 weeks of aerobic exercise	12 weeks

Secondary Outcome Measures

Name	Time	Method
anthropometric parameters	12 weeks	body weight, waist circumference, body fat percentage, visceral fat area
biochemical parameters	12 weeks	HbA1c, apolipoprotein B, free fatty acid
energy expenditure	12 weeks	activity energy expenditure, total energy expenditure

Trial Locations

Locations (1)

Eulji University School of Medicine; 🇰🇷 Seoul, Korea, Republic of