Consistencies in Responses to Sodium Bicarbonate?

Not Applicable

Completed

• Conditions: Sports Nutritional Physiological Phenomena
• Interventions: Dietary Supplement: sodium bicarbonate; Dietary Supplement: calcium carbonate

• Registration Number: NCT02474628
• Lead Sponsor: University of Sao Paulo

Brief Summary

Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. The investigators aim to determine the consistency of metabolic and exercise responses following repeated administration of sodium bicarbonate (SB). Design and Methods: 15 physically active males will complete six cycling capacity tests at 110% of maximum power output (CCT110%) following ingestion of either 0.3 g∙kg-1Body Mass of SB (4 trials) or placebo (PL, 2 trials). Blood pH, bicarbonate, base excess and lactate will be determined at baseline, pre-exercise, post-exercise and 5-min post-exercise. Total work done (TWD) will be recorded as the exercise outcome.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2015-06
• Study First Submitted: 2015-06-08
• Study First Submitted QC: 2015-06-17
• Last Update Submitted: 2015-06-17
• Study First Posted: 2015-06-18
• Last Update Posted: 2015-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 15

Inclusion Criteria

• recreationally active males

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Exclusion Criteria

• use of dietary supplements in the past 6 months
• the presence of any musculoskeletal disorder
• the use of anabolic steroids

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Sodium bicarbonate	sodium bicarbonate	0.3 g∙kg-1body mass of sodium bicarbonate
Placebo	calcium carbonate	0.3 g∙kg-1body mass of calcium carbonate

Primary Outcome Measures

Name	Time	Method
blood pH	5 min after a physical exercise test

Secondary Outcome Measures

Name	Time	Method
blood lactate	5 min after a physical exercise test
blood bicarbonate	5 min after a physical exercise test
anaerobic exercise capacity	4 hours after supplementation	as assessed by cycling capacity tests at 110% of maximum power output

Trial Locations

Locations (1)

University of Sao Paulo; 🇧🇷 Sao Paulo, Brazil