Improving early detection and intervention for young infants at high risk of neurodevelopmental delay and disability in Uganda

Not Applicable

Completed

• Conditions: eurodevelopmental impairment and disability; Nervous System Diseases; Neurodevelopmental impairment and disability

• Registration Number: ISRCTN44380971
• Lead Sponsor: MRC/UVRI Uganda Research Unit on AIDS

Brief Summary

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31601606 (added 14/10/2019) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36177453/ (added 03/10/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-16
• Study Completion: 2019-09-30
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 126

Inclusion Criteria

Infants and their caregivers must satisfy the following inclusion criteria:
1. Infant aged 6-9 months
2. Infant has moderate-severe developmental impairment defined as a Developmental Quotient (DQ) on the Griffiths Mental Developmental Scales of <70 and/or HINE score <60
3. Informed written consent is provided by caregiver

Exclusion Criteria

1. Condition requiring inpatient treatment
2. Caregivers not willing or unable to attend the full programme
3. Main residence outside Nakaseke district or >20km from Mulago Hospital
4. No caregiver informed written consent
5. Accompanying parent or guardian does not speak or understand Luganda or English

Study & Design

• Study Type: Interventional
• Study Design: Not specified