Prediction of Efficacy of Oral Trileptal (Oxcarbazepine) by Intravenous Lidocaine Infusion in Patient with Neuropathic Pain Syndrome

Phase 2

Active, not recruiting

• Conditions: Peripheral neuropathic pain, diabetic neuropathy, post herpetic neuralgia, trigeminal neuralgia, phanton limb pain, nerve injury pain; oxcarbazepine, oral Trileptal, prediction efficacy, lidocaine infusion&#44

• Registration Number: TCTR20141029001
• Lead Sponsor: Siriraj Research and Development Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-10-29
• Study Completion: 2015-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1.Have a symptom of peripheral neuropathic pain
2.Age 18 - 65 years
3.Have pain score numerical rating scales (NRS)>5

Exclusion Criteria

1) Pregnancy, 2) Previous carbarmazepine, oxcarbazepine and lidocaine treatment, 3) Allergy to oxcarbazepine, carbamazepine or lidocaine, 4) Patient with cancer, 5) Patient with impaired mental status or psychosis. 6) Patient with uncontrolled medical conditions such as Child-Pugh B, CrCl<50 ml/min, arrhythmia.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pain reduction post lidocaine,post oxcarbazepine 3 time point, baseline, post lidocaine, post oxcarbazepine Numerical rating scale baseline,post lidocaine infusion and posy oxcarbazepine

Secondary Outcome Measures

Name	Time	Method
evaluate the efficacy and side effects of oxcarbazepine in peripheral neuropathic pain post oxcarbazepine side effect of oxcarbazepine