Wetenschappelijk vervolgonderzoek Turner Oxandrolon Studie.
Recruiting
- Conditions
- Turner syndroom (Syndroom van Turner)The main study parameters are: height, body proportions, body composition, symptoms and signs of virilization, glucose tolerance, lipid profile, cardiac conduction abnormalities, liver and thyroid function, (neuro)psychological function and quality of life.
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 130
Inclusion Criteria
1. Completion of the original TOS protocol at least 6 months prior to the study visit;
2. Age >18 years.
Exclusion Criteria
1. Patients who have participated in another experimental drug study within two months of entry into the present study;
2. Malignant or severely disabling disease;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Final adult height.
- Secondary Outcome Measures
Name Time Method 1. Body proportions and composition;<br /><br>2. Metabolic parameters;<br /><br>3. Virilizing effects;<br /><br>4. Cardiovascular, liver and thyroid function;<br /><br>5. (Neuro)psychological function;<br /><br>6. Quality of life.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Oxandrolone's effects on height and body composition in Turner Syndrome patients?
How does Oxandrolone compare to growth hormone and estrogen therapy in improving metabolic parameters in Turner Syndrome?
Which biomarkers correlate with virilization symptoms and cardiac conduction abnormalities in Turner Syndrome follow-up studies?
What adverse events are associated with long-term Oxandrolone use in Turner Syndrome, and how are they managed?
Are there synergistic effects of combining Oxandrolone with testosterone derivatives in Turner Syndrome treatment?