Topical Intranasal Tranexamic Acid in Epistaxis

Phase 3

Recruiting

• Conditions: Epistaxis; R04.0; Epistaxis.

• Registration Number: IRCT20210403050815N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

Aged 18 or over
Presenting to the Ear, Nose, and Throat emergency department (ED) with spontaneous, atraumatic anterior epistaxis, unresolved with simple first aid

Exclusion Criteria

Hemodynamically unstable
Known allergy to tranexamic acid
Lacking capacity or unwilling to give consent
Known nasopharyngeal, nasal cavity or paranasal malignancy
Pregnancy
Already undergone prehospital nasal packing
Prisoners
Epistaxis caused by trauma (excluding simple nose picking)
Any Known bleeding disorders
Any recent use of anticoagulation drugs

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eed for use of anterior nasal packing. Timepoint: at any time during that ED attendance after initial management. Method of measurement: determined by clinical judgment.

Secondary Outcome Measures

Name	Time	Method
eed for use of electrical cauterization. Timepoint: at any time during ED attendance after initial intervention. Method of measurement: determined by clinical judgment of physician.;Rebleeding within 24 hours after presenting to ED. Timepoint: within 24 hours after treatment. Method of measurement: self-statement of the patient with telephone call.;Rebleeding within 1-7 days after presenting to ED. Timepoint: 1-7 days after presenting to ED. Method of measurement: self-statement of the patient with telephone call.;ED stay more than 2 hours. Timepoint: from presenting to ED to leaving the hospital. Method of measurement: This outcome variable will be evaluated and reported as a qualitative variable. The patients who have been discharged from ED after 2 hours from the presentation will be considered as positive cases for this variable.