Optimale voedingsroute na een oesofagusresectie

Recruiting

Conditions: esophageal cancer, esophagectomy, nutrition, postoperative complications, pulmonary complications, anastomic leakage, Quality of life

Registration Number: NL-OMON21339

Lead Sponsor: Catharina Hospital Eindhoven

Brief Summary: 1 Weijs TJ, Berkelmans GH, Nieuwenhuijzen GA, et al. Routes for early enteral nutrition after esophagectomy. A systematic review. Clin Nutr 2015; 34(1): 1-6.

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 148

Inclusion Criteria

Patients that undergo a (minimally invasive) esophagectomy with intrathoracic anastomosis.
- written informed consent
- age >18 years

Exclusion Criteria

- Inability for oral intake
- Inability to place a surgical feeding jejunostomy
- Mental retardation
- Swallowing disorder
- Achalasia
- Malnutrition (defined as >15% weight loss just before start of the surgery)

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Functional recovery

Secondary Outcome Measures

Name	Time	Method
- Pulmonary complications (Pneumonia, Acute respiratory distress syndrome (ARDS), respiratory insufficiency requiring treatment) <br>- Anastomotic leakage (clinically and amylase levels in drain fluid)<br>- Nutritional status (weight loss, intake) <br>- Need for parenteral feeding/ placement of a nasojejunal feeding tube <br>- Need for additional surgical, radiological or endoscopic interventions <br>- 30-day surgical complications (classified according to Clavien-Dindo) <br>- Other complications requiring treatment (i.e. urinary tract infection) <br>- Need for ICU admission and total length of ICU stay<br>- Quality of life