Urodynamics of Suprasacral Spinal Cord Injury Patients

Completed

• Conditions: Spinal Cord Injuries

• Registration Number: NCT04642170
• Lead Sponsor: Second Affiliated Hospital of Wenzhou Medical University

Brief Summary

The medical records of 215 patients with spinal cord injury(SCI) at the Department of Rehabilitation Medicine of the 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou, China were evaluated between January 1, 2016 and December 20, 2019. According to the inclusion criteria and exclusion criteria, 101 patients were included. The patients were dichotomized into two groups: complete SCI group and incomplete SCI group, based on the American Spinal Injury Association Guidelines Impairment Scale (AIS) .The investigators retrospectively collected records of urodynamic evaluations of this patients and then analyze the urodynamic parameters,including detrusor overactivity (DO), bladder compliance (BC), bladder-filling sensation, maximum cystometric capacity (MCC), detrusor external sphincter dyssynergia (DESD), maximum urinary flow rate (Qmax), detrusor pressure at a maximum urinary flow rate(PdetQmax).

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-01
• Primary Completion: 2019-12-20
• Study Completion: 2019-12-20
• Status Verified: 2020-11
• Study First Submitted: 2020-11-14
• Study First Submitted QC: 2020-11-23
• Last Update Submitted: 2020-11-23
• Study First Posted: 2020-11-24
• Last Update Posted: 2020-11-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 101

Inclusion Criteria

Not provided

Exclusion Criteria

The patient with voiding dysfunction before the injury were excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
bladder compliance (BC)	0-365 days after injury	bladder compliance in ml/cmH2O,one of the urodynamic parameters
bladder-filling sensation	0-365 days after injury	bladder-filling sensation,one of the urodynamic parameters
detrusor overactivity (DO)	0-365 days after injury	detrusor overactivity in milliliter,one of the urodynamic parameters

Secondary Outcome Measures

Name	Time	Method
maximum cystometric capacity (MCC)	0-365 days after injury	maximum cystometric capacity in milliliter,one of the urodynamic parameters
detrusor external sphincter dyssynergia (DESD)	0-365 days after injury	detrusor external sphincter dyssynergia,one of the urodynamic parameters