The retinal nerve fibre layer in patients with multiple sclerosis
- Conditions
- 10012303multiple sclerosis
- Registration Number
- NL-OMON30379
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
- age eightteen years or older
- written informed consent
- patients: diagnosis of multiple sclerosis, according to the McDonal criteria
Exclusion Criteria
- current or previous ophthalmologic disease other than optic neuritis
- contraindication for the use of mydriaticum: known allergy against tropicamide, known narrow-angle glaucoma.
- impaired visus as measured with visus examination cards (Snellen)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- The difference in diameter of the retinal nerve fibre layer between the<br /><br>groups BMS, SPMS, PPMS and healthy control persons.</p><br>
- Secondary Outcome Measures
Name Time Method <p>- The correlation of clinical measures of disability and diameter of the<br /><br>retinal nerve fibre layer.<br /><br>- The correlation of MSSS scores and diameter of the retinal nerve fibre layer.</p><br>