TCTR20230713010招募中不适用
The Characteristic of Retinal Nerve Fiber Layer Thickness in Advance and End-stage Glaucoma using Spectral Domain Optical Coherence Tomography
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1. Glaucoma patients older than 18 years.
- •2. The patient was diagnosed with glaucoma.
- •3. Advanced glaucoma patients include glaucoma patients with visual field effect, less than 10 degree and visual acuity more than 6/60 from automated perimetry test (Automated perimetry results must have the reliability index according to fixation loss, false negative and false positive less than 30%.
- •4. Patients with end-stage glaucoma include glaucoma patients with visual acuity less than light perception. Automated perimetry is not possible in a patient with end-stage glaucoma group because low vision. Therefore, the patient was definitely end-stage glaucoma without other affecting the optic nerve (optic nerve head and retinal nerve fiber layer thickness). This group, patients had only one eye of end-stage glaucoma, and the other side must have visual acuity more than 6/60 to be able to read and sign the inform consent form by themself.
- •5. The patient had a visual field examination (only advance glaucoma group) and spectral domain optical coherence tomography with a time difference, not longer than 6 months.
排除标准
- •1. Glaucoma patients who can not cooperate with automated perimetry test (only advanced glaucoma group) and Spectral domain optical coherence tomography test (open eyelid, look straight, remain still for about 1 minute and no vision required)
- •2. Spectral domain optical coherence tomography results are unreliable, signal strength less than 6.
- •3. Patients with retinal disease that affects retinal nerve fiber layer thickness
- •4. Patients with disease non-glaucomatous optic neuropathy
- •5. Patients with secondary glaucoma
- •6. Patients with other diseases that is not glaucoma received therapeutic drugs that affect the optic nerve and retinal nerve fiber layer thickness, such as chloroquine.
- •7. Patients with ocular inflammation or uveitis.
- •8. Patients who underwent intraocular surgery within 3 months prior to examination by Spectral domain optical coherence tomography and Automated perimetry.
- •9. Cannot read and sign the inform consent form by themself. the other side must have visual acuity less than 6/60.
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