A prospective randomised controlled trial in the treatment of anal fissures; Botulin-A Toxin versus Topical Diltiazem: BOTTOM-trial.
Recruiting
- Conditions
- Anal fissure (NLD: anale fissuur).
- Registration Number
- NL-OMON29443
- Lead Sponsor
- B.A. Twigt, E.A te Velde, L. Stoker, E. Kuck, A. Pronk
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 164
Inclusion Criteria
Chronic anal fissure, without previous therapy.
Exclusion Criteria
1. Allergy to botuline A toxine and Diltiazem;
2. Cardiovascular disease:
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Healing of fissure.
- Secondary Outcome Measures
Name Time Method Costs and adverse events.