Effect of Albumin in Stroke

Not Applicable

• Conditions: Ischemic Stroke.; Cerebral infarction due to thrombosis of cerebral arteries

• Registration Number: IRCT201008214606N1
• Lead Sponsor: JondiShapur Ahvaz university of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

patients with acute ischemic stroke; age between 18 to 83 years old; NIH stroke scale more than 5; transfusion of albumin with in 5 hour and infarction in MCA area.
Exclusion criteria: heart failure(CHF) in 6 last months; concurrent valvular heart disease with CHF; stenosis of aorta or aortic valve; open heart surgery; acute MI in last 6 month; MI symptoms; Troponin increase in hospitalization (>0.1mcg/l); doubt of aorta dakshin in hospitalization; acute heart arythmia cause of hemodynamic transience; physical examination results include: JVP>4cm on top of sternal angle S3, Tachycardia in relaxation cause Congestive Heart failure (HR>100/min), hepatojugular abnormal reflex
specific C-xray of Pulmonary edema
Pitting edema of the lower extremities that can cause congestive heart failure; acute or chronic lung disease requiring supplemental oxygen therapy is intermittent or permanent; fever T>37.5; serum creatinine > 2 mg / dl.; excessive dehydration; evidence of cerebral hemorrhage on CT or MRI (Intracranial hematoma / SAH / epidural hemorrhage / acute or chronic subdural hematoma); allergy to albumin
17.Allery to latex; Hgb < 7.5 g / dl; pregnancy / lactation / positive pregnancy test (women of childbearing age have a negative test for pregnancy before albumin administration ); medical evidence of any serious or life-threatening condition that interfere with 3-month follow-up trial or assessing patients'outcome or Treatment with the contraindica albumin is harmful; participation in another clinical trial data yet; occurrence of stroke due to complications of hospitalization for other conditions or complications due to a procedure; not afford to buy albumin and lacunar Infarction.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient Functional Outcome. Timepoint: At admission time,after one week and after 3 month. Method of measurement: Barthel Scale, Modified Rankin Scale.

Secondary Outcome Measures

Name	Time	Method
Morbidity and Mortality. Timepoint: At the admision, after one week and 3 month. Method of measurement: Registration of mortality.;Drug side effects. Timepoint: At the admision,after one week and 3 month. Method of measurement: Drug side effects chart.