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Distal renal tubular acidosis in Sjögren Syndrome and postmenopausal osteoporosis

Withdrawn
Conditions
renal tubular acidosis
10003816
10005959
10029149
Registration Number
NL-OMON36946
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Withdrawn
Sex
Not specified
Target Recruitment
176
Inclusion Criteria

Diagnosed with postmenopausal osteoporosis
Diagnoses of Sjögren syndrome based on American-Europenean criteria
DEXA-scan performed within the last year
DEXA-scan with a T-score < -2,5
Age older than 18 years
No secondary cause known of osteoporosis
No previous record of urinary pH screening

Exclusion Criteria

Secondary osteoporosis
Age below 18
DEXA-scan with T > -2,5

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>We intend to determine the prevalence of dRTA and/or disorders in calcium<br /><br>metabolism in pSS and postmenopausal osteoporosis. Additionally, we intend to<br /><br>study the underlying pathogenetic mechanism. The results of alkali treatment<br /><br>will be monitored.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>na</p><br>
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