Distal renal tubular acidosis in primary Sjögren syndrome

Completed

• Conditions: type 1 RTA; urinary acidificaiton problem localized in the kidney; 10003816; 10005959; 10038430

• Registration Number: NL-OMON39002
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 62

Inclusion Criteria

The pSS patients have to meet the following inclusion criteria:
• Age older than 18 years
• Diagnosis based on the Revised international classification criteria for Sjögren syndrome
• No secondary auto-immune disease (SLE, Rheumatoid Arthritis)

Exclusion Criteria

The exclusion criteria are also mentioned in the inclusion criteria.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoint of this study is to determine the prevalence of dRTA in pSS<br /><br>using two acidification tests. Additionally, the prevalence of an abnormal BMD<br /><br>will also be determined in the same group. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoint of this study is the calculation of the sensitivity and<br /><br>specificity of the FF test.</p><br>