MedPath

VEGF in Iris Tissue in Primary Congenital Glaucoma

Not Applicable
Conditions
Iris
Registration Number
NCT05484050
Lead Sponsor
Hassan Lotfy Fahmy
Brief Summary

Estimation of vascular endothelial growth factor (VEGF) in iris tissue specimen in primary congenital glaucoma through Immunohistochemistry.

Detailed Description

Combined trabeculotomy with mitomycin C will done in infants with primary congenital glaucoma with histopathological examination of the the peripheral iris tissue specimen and vascular endothelial growth factor (VEGF) estimation in iris tissue specimen through Immunohistochemistry.

Estimation of vascular endothelial growth factor (VEGF) in iris tissue specimen taking from ocular trauma or congenital cataract used as control.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  • primary congenital glaucoma
Exclusion Criteria
  • Infants with history of previous surgery.
  • Secondary glaucoma.
  • Glaucoma associated with other congenital anomalies.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
VEGF6 month

Estimation of VEGF grade in iris tissue through Immunohistochemistry, The grades is arranged from 0 to 5, with 0 being the lowest level and 5 being the highest level

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hassan Lotfy

🇪🇬

Assiut, Egypt

Hassan Lotfy
🇪🇬Assiut, Egypt

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.