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A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies

Completed
Conditions
Actinic Keratosis
Interventions
Drug: Lesion count
Registration Number
NCT00953732
Lead Sponsor
Peplin
Brief Summary

This study is designed to follow up patients who have achieved complete clearance of AK lesions at the Day 57 visit having completed the PEP005-016 or PEP005-025 studies over a 12 month period to assess both recurrence of Actinic Keratosis (AK) lesions and long term safety in the selected treatment area.

Detailed Description

A 12 month long-term follow-up study of patients who have achieved complete clearance of AK lesions at the Day 57 in the Phase 3 studies PEP005-016 or PEP005-025.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
117
Inclusion Criteria
  • Patient must have achieved complete clearance of AK lesions (lesion count = 0) at Day 57 in one of the following Peplin AK clinical studies: PEP005-016 or PEP005-025
  • Patient has provided informed consent documented by signing the Informed Consent Form (ICF) prior to any study-related procedures
Exclusion Criteria
  • Concurrent participation in another research study which would involve the selected treatment area (except for any post-study follow-up visits for previous Peplin AK study)
  • Early termination from study PEP005-016 or PEP005-025

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
1Lesion count-
Primary Outcome Measures
NameTimeMethod
Summarize treatment area recurrence of AK lesions, in the selected treatment area12 months
Secondary Outcome Measures
NameTimeMethod
Summarize long-term safety data(incidence of AEs in the treatment area)12 months

Trial Locations

Locations (41)

Pedia Research LLC

🇺🇸

Owensboro, Kentucky, United States

Burke Pharmaceutical Research

🇺🇸

Hot Springs, Arizona, United States

Dermatology Research Associates

🇺🇸

Nashville, Tennessee, United States

Skin Surgery Medical Group Inc.

🇺🇸

San Diego, California, United States

Dermatology Specialists Inc

🇺🇸

Oceanside, California, United States

Conant Medical Group

🇺🇸

San Francisco, California, United States

University of Miami, Skin Research Camp

🇺🇸

Miami, Florida, United States

North Florida Dermatology Associates, PA

🇺🇸

Jacksonville, Florida, United States

Atlanta Dermatology, Vein & Research Center, LLC

🇺🇸

Alpharetta, Georgia, United States

Medaphase Inc

🇺🇸

Newnan, Georgia, United States

Glazer Dermatology

🇺🇸

Buffalo Grove, Illinois, United States

Altman Dermatology Associates

🇺🇸

Arlington Heights, Illinois, United States

Laser Skin Surgery Center of Indiana

🇺🇸

Carmel, Indiana, United States

Hamzavi Dermatology

🇺🇸

Fort Gratiot, Michigan, United States

Minnesota Clinical Study Center

🇺🇸

Fridley, Minnesota, United States

Karl G. Heine Dermatology

🇺🇸

Henderson, Nevada, United States

Skin Specialists, PC

🇺🇸

Omaha, Nebraska, United States

Academic Dermatology Associates

🇺🇸

Albuquerque, New Mexico, United States

Mount Sinai School of Medicine

🇺🇸

New York, New York, United States

Dermatology, Laser Vein Specialists of the Carolinas

🇺🇸

Charlotte, North Carolina, United States

Oregon Medical Research

🇺🇸

Portland, Oregon, United States

DermResearch, Inc.

🇺🇸

Austin, Texas, United States

Suzanne Bruce and Associates, The Center for Skin Research

🇺🇸

Houston, Texas, United States

Progressive Clinical Research

🇺🇸

San Antonio, Texas, United States

Center for Clinical Studies

🇺🇸

Webster, Texas, United States

The Education and Research Foundation

🇺🇸

Lynchburg, Virginia, United States

Virginia Clinical Research, Inc

🇺🇸

Norfolk, Virginia, United States

Premier Clinical Research

🇺🇸

Spokane, Washington, United States

St George Dematology and Skin Cancer Centre

🇦🇺

Kogarah, New South Wales, Australia

The Skin Centre

🇦🇺

Benowa, Queensland, Australia

South East Dermatology, Belmont Specialist Centre

🇦🇺

Carina Heights, Queensland, Australia

Center for Dermatology

🇺🇸

Fremont, California, United States

Deaconess Clinic, Inc

🇺🇸

Evansville, Indiana, United States

Dawes Fretein Clinical Research Group, LLC

🇺🇸

Indianapolis, Indiana, United States

The Indiana Clinical Trials Center, PC

🇺🇸

Plainfield, Indiana, United States

Dermatology Associates of Rochester, PC

🇺🇸

Rochester, New York, United States

Wake Research Associates

🇺🇸

Raleigh, North Carolina, United States

J & S Studies, Inc.

🇺🇸

College Station, Texas, United States

Dermatology Associates of Tyler

🇺🇸

Tyler, Texas, United States

Southderm Pty Ltd

🇦🇺

Kogarah, New South Wales, Australia

Dermatology Research Center, Inc.

🇺🇸

Salt Lake City, Utah, United States

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