The randomized controlled trial of the R-THP-COP therapy versus R-CHOP therapy for treatment of elderly patients with untreated advanced stage diffuse large B-cell lymphoma, Phase II and III study
Phase 2
- Conditions
- diffuse large B-cell lymphoma
- Registration Number
- JPRN-UMIN000007282
- Lead Sponsor
- Gifu University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients with HIV or HTLV-1. 2)Patients with uncontrolled intercurrent illness including, but not limited to, malignant hypertension, congestive heart failure, coronary insufficiency, a new onset of myocardial infarction within 3 months , liver cirrhosis, uncontrolled hyperglycemia, renal failure, pulmonary fibrosis, or bleeding tendency. 3)Patients with another active malignancy 4)Patients who are pregnant or lactating, or have an intention to get pregnant 5)Patients with severe mental disease. 6)Patients who have had chemotherapy or radiotherapy prior to entering the study. 7)Patients who are judged inappropriate for the entry into the study by the principle doctor.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Remission rate
- Secondary Outcome Measures
Name Time Method response rate, survival time, safety