Prospective randomized controlled study of CRRT hemofilters for the treatment of acute kidney injury (AKI)
Not Applicable
- Conditions
- Acute kidney injury (AKI)
- Registration Number
- JPRN-UMIN000016105
- Lead Sponsor
- Wakayama Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
- age less than 18 - pregnant women - chronic hemodialysis patients or patients who received RRT before randomization - end stage cancer patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 28-day mortality
- Secondary Outcome Measures
Name Time Method 60-day mortality. Changes of SOFA score at 3 and 7 days after CRRT. Changes of plasma IL-6 levels at 1, 3, and 7 days after CRRT. Changes of lactate levels at 1, 3, and 7 days after CRRT. ICU free-days at Day 28. RRT free-days at Day 28. Progression to ESRD requiring maintenance hemodialysis. (subgroup analysis) septic AKI and non-septic AKI. with and without endotoxin removal hemoperfusion therapy.