on-invasive measurement of radicals in skin after exposure to tobacco smoke in vivo.
- Conditions
- healthy volunteers
- Registration Number
- DRKS00029235
- Lead Sponsor
- Charité-Universitätsmedizin Berlin, Dermatologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 25
The studies will be performed on study participants who are
- are > 18 years old and have no skin diseases
- have given written informed consent
- have a skin type of I-III (Fitzpatrick)
- Informed about the aims of the study and the nature of the examinations
Exclusion Criteria:
- Minors
- Persons wearing metallic implants in the area of the forearm (screws, pins, etc. )
- Persons wearing tattoos in the area of the inner forearm
- nursing mothers and women with known pregnancy
- known skin diseases
- skin type >III (Fitzpatrick)
- intensive sun exposure on the skin areas to be irradiated on the inner forearm within the last 14 days before the irradiation date
- test persons who are shorter than 1,60m
- Subjects who are not able to make decisions on their own responsibility
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection of radicals after exposure to cigarette smoke using confocal Raman microscopy (CRM) .
- Secondary Outcome Measures
Name Time Method Demonstration of the protective effect against cigarette smoke-induced radical formation by a cream formulation.