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The Effects of Nebulized Budesonide and Dexamethasone on Patients Using Tube for Ventilation.

Not Applicable
Conditions
Condition 1: Head trauma. Condition 2: Loss of Consciousness. Condition 3: Surgery. Condition 4: Poisoning.
Crushing injury of head, part unspecified
Coma, unspecified
Complication of surgical and medical care, unspecified
Drugs affecting uric acid metabolism
Registration Number
IRCT2017061734598N1
Lead Sponsor
Vice Chancellor for research of Isfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
270
Inclusion Criteria

the age range of 65-18 years; at least 48 hours of intubation; admission to intensive care unit and patient or his family’s consent to participate in the study.
Exclusion criteria: receiving corticosteroids; respiratory disease such as asthma or chronic lung disease; chronic consumption of NSAIDs.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Oxygen saturation. Timepoint: At the beginning of the study (zero hour) and 12, 24, 36 and 48 hours after intubation. Method of measurement: Pulse oximetry device.;Mean Arterial Pressure. Timepoint: At the beginning of the study (zero hour) and 12, 24, 36 and 48 hours after intubation. Method of measurement: Cardiac monitoring.;Heart Rate. Timepoint: At the beginning of the study (zero hour) and 12, 24, 36 and 48 hours after intubation. Method of measurement: Cardiac monitoring.;Cuff Leak Rate. Timepoint: At the beginning of the study (zero hour) and 12, 24, 36 and 48 hours after intubation. Method of measurement: (Average volume of exhaust flow at 3 breaths with low current volume - Current volume of the device)/Current volume of the device =CLR.
Secondary Outcome Measures
NameTimeMethod
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