euromodulation for reducing neurogenic detrusor overactivity in spinal cord injury

Not Applicable

Completed

• Conditions: Specialty: Renal disorders, Primary sub-specialty: Renal disorders; Urological and Genital Diseases; Renal disorders

• Registration Number: ISRCTN99373118
• Lead Sponsor: Royal National Orthopaedic Hospital NHS Trust

Brief Summary

2019 results in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951414/ (added 01/10/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-07-07
• Study Completion: 2019-09-13
• Last Update Posted: 12 October 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. Spinal Cord Injured
2. Aged 18-70
3. Male or Female
4. Injury sustained >6 months ago
5. Urodynamically proven Neurogenic Detrusor Overactivity

Exclusion Criteria

1. Recipient of intra-detrusor botulinum toxin injections within the last 6 months
2. Previous surgical intervention on bladder/sphincters
3. Showing positive leucocytes and nitrites on urinalysis on the day of investigation
4. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bladder overactivity is measured using standard urodynamics to measure bladder pressures and volumes without stimulation present (control), then with stimulation over one of four sites (experimental).

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures