Titrating to the optimal pressure. Is transcutaneous electromyography of the diaphragm a good measurement to determine the optimal respiratory support, during continuous positive airway pressure (CPAP), in pre-term born neonates.

Completed

• Conditions: respiratory support; support of breathing; 10028971

• Registration Number: NL-OMON45956
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 19

Inclusion Criteria

- pre-term neonates admitted to the NICU ward.
- supported with CPAP
- clinically stable, for at least 24 hours
- gestational age above 26 weeks and under 32 weeks

Exclusion Criteria

- neonates with congenital anomalies
- respiratory support other than CPAP
- gestational age under 26 weeks and above 32 weeks

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Changes in dEMG signal ( in uV); measuring the maximal, minimal and delta (<br /><br>difference between de maximum and minimum value) values of the dEMG during the<br /><br>levels of CPAP.<br /><br>Silverman/ Anderson score measured at 5 and 10 minutes per block.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Vital parameters: heart frequency, saturation, apnea, breathing frequency </p><br>