Periodontal changes during pregnancy with and without risk for preterm delivery
Recruiting
- Conditions
- periodontal changes
- Registration Number
- DRKS00000282
- Lead Sponsor
- niklinik Freiburg, Abteilung für Zahnerhaltungskunde und Parodontologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
Study group 1: Singleton pregnancy before 32nd week of gestation, in-patient due to risk for preterm delivery
Study group 2: Singleton pregnancy before 20th week of gestation, no risk for preterm delivery
Control group: no pregnancy, no hormonal contraception
Maximum of 20% smokers in each group
Exclusion Criteria
Study group 1 and 2:
multiple pregnancy
amniorrhoea
menstruation like bleeding
risk for endocarditis
Study group 2: risk for preterm delivery
Control group: Pregnancy, hormonal contraception
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Raising of oral clinical parameters (Plaque-Index (PI), Gingiva-Index (GI) and Periodontal Screening Index (PSI) if PSI Code 3 and 4 periodontal status in addition) using a periodontal probe and visual as well as microbiological analyses with a molecular genetic test system and bacterial culture at time between 24th and 32nd week of gestation and maximal 4 weeks after delivery. Pregnant women without risk for preterm delivery will be emamined between 15th and 20th week of gestation in addition.
- Secondary Outcome Measures
Name Time Method Analyses and comparison of intraoral and vaginal microflora using bacterial culture of pregnant women with risk for preterm delivery between 24th and 32nd week of gestation.