Comparative study of the outcome of oral versus nasal intubation in neonates and infants undergoing cardiac surgery
Phase 1
Recruiting
- Conditions
- Anaesthesia
- Registration Number
- PACTR202004476254378
- Lead Sponsor
- Mansoura university children hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
This study will be conducted on 200 patients of either sex with their age less than one year submitted for on pump cardiac surgery
Exclusion Criteria
Patients will be excluded from the current study in case of refusal of their guardians, redo cardiac surgery, congenital deformity of the nose and palate, presence of contraindication to nasal intubation, coagulation disorders, renal, hepatic or pulmonary disease, heart failure and moderate to severe pulmonary hypertension.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total dose of postoperative fentanyl consumption during the first postoperative 24 hours.
- Secondary Outcome Measures
Name Time Method 1- Maximum heart rate [HR] and invasive mean arterial blood pressure [MAP] during intubation.<br>2-Time that will be taken for intubation (seconds). We will define an intubation duration as starting when the bag and mask ventilation stopped before intubation and terminating when the positive pressure ventilation (PPV) started after inserting the ET tube.<br>3-Minimum oxygen saturation during intubation.<br>4- Number of nasal intubation trials and number of failed nasal intubation. <br>5- Accidental extubation either spontaneous or during trans esophageal echo probe manipulation. <br>6- Occurrence of traumatic complications of nasal intubation (epistaxis).<br>7- Time to extubation (hours). <br>8- Intensive care unit (ICU) and hospital length of stays. <br>9- Post-operative complications (the need for re-intubation, stridor, pneumonia, wound infection) <br>