CTRI/2025/06/088558尚未招募4 期
"A PROSPECTIVE RANDOMIZED STUDY TO COMPARE THE EFFECT OF FRACTIONATED VERSUS BOLUS DOSE OF INJECTION 0.5% BUPIVACAINE AND FENTANYL IN SPINAL ANAESTHESIA FOR LOWER EXTREMITIES ORTHOPAEDIC SURGERY."
Dr Ashwini solanki1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2025年6月30日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Expected early onset of sensory and motor blockage and prolonged duration of analgesia and more hemodynamic stability in fractionated dose group
研究概览
简要总结
This is a prospective comparitive study comparing fractionated versus bolus dose of injection 0.5% hyperbaric bupivacaine with fentanyl in spinal anaesthesia for lower limb surgeries.In this study we are comparing sensory blockage,motor blockage,post operative analgesia, hemodynamic changes and adverse effects in both group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patients undergoing lower limb surgeries.
- •Age between 18 to 60 years ,ASA grade I and II.
排除标准
- •Age less than 18 years of age and more than 60 years Patient refusal ASA III & IV Infection at the site of injection Patient having hereditary coagulopathy, raised ICT, severely altered mental status, spinal deformities, aortic stenosis, BMI more than 35 kg/m2 and thromboprophylaxis, allergy to spinal anaesthesia.
结局指标
主要结局
Expected early onset of sensory and motor blockage and prolonged duration of analgesia and more hemodynamic stability in fractionated dose group
时间窗: 24 Hours
次要结局
- Expected better post operative analgesia and lesser side-effects(24 Hours)
研究者
Dr Ashwini solanki
Gajra Raja Medical College Gwalior
研究点 (1)
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