Safety of a long-term endoscopic surveillance protocol for serrated polyposis patients
Recruiting
- Conditions
- colorectal cancer, serrated polyposis syndrome
- Registration Number
- NL-OMON28738
- Lead Sponsor
- Academic medical centre, Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
HPS patients defined as:
> 5 HPs/SSA proximal to the sigmoid, of which 2 > 10 mm in diameter, or more than 20 HPs/SSAs distributed throughout the colon.
Exclusion Criteria
Carriers of a germline mutation in the MutYH or APC gene and individuals who have undergone a total colonic resection.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Incidence of interval colorectal cancer during protocolled endoscopic surveillance of SPS patients
- Secondary Outcome Measures
Name Time Method - Incidence and characteristics of polyps found during endoscopic surveillance of SPS patients<br /><br>- The ratio of annual and biennial surveillance advise <br /><br>- Incidence of conversion to preventive colorectal surgery<br /><br>- Incidence of post-colonoscopy complications<br>