Comparison of efficacy of pre-emptive and post operative lornoxicam in mandibular third molar surgeries - A split mouth study.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 1) The efficacy of Lornoxicam as a pre emptive and post operative analgesic.
研究概览
简要总结
After obtaining approval and clearance from the Institutional Ethical Committee the patients fulfilling the inclusion criteria will be enrolled for the study. Patients requiring surgical removal of impacted third molars on mandibular arch are taken up after radiographical assessment is done. Surgical site will be randomly divided into two groups Group A will receive tablet Lornoxicam eight mg one hour before the surgery and Group B will receive tablet Lornoxicam eight mg one hour after the surgery. Patient will be asked to rinse the oral cavity thoroughly and standard painting and draping of the patient will be done. The procedure will be performed under Local anesthesia two percent lignocaine with adrenaline. Classical inferior alveolar nerve block will be given. Once the anesthesia is achieved surgical assess will be gained. Bone will be removed around the tooth under copious irrigation. The crown and roots will be sectioned if necessary. Third molar will be removed surgically with minimal trauma to investing tissues. Socket toileting will be done followed by primary closure. Antibiotics and Analgesics will be prescribed post operatively. Post operative instructions will be given and is instructed to consume first rescue analgesic tablet Lornoxicam eight mg as soon as the patient experiences pain. The patient will be assessed for pain post operative hours through questionnaire. Patient satisfaction will be recorded using Likert five point scale post operatively
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with bilaterally similar impacted mandibular third molars.
- •Patients classified under ASA I and ASA II requiring surgical extraction of bilaterally similar impacted mandibular third molars.
- •Patient willing to sign the informed consent.
排除标准
- •Patients with erupted third molars.
- •Patients classified under ASA III and ASA IV.
- •Patients who have consumed any other analgesics in 24 hours before surgery.
- •Patients with gastritis and peptic ulcers.
- •Pregnant patients.
- •Patients with psychiatric illness.
- •Patients with infections like pericoronitis, pericoronal abscess, etc.
结局指标
主要结局
1) The efficacy of Lornoxicam as a pre emptive and post operative analgesic.
时间窗: 1)The efficacy of Lornoxicam as a pre emptive analgesic. | 2)The efficacy of Lornoxicam as a post operative analgesic. | 3)Pain at 2nd, 4th, 6th, 12th, and 24th hour post operatively using VAS. | 4)The number of rescue analgesics taken within 24 hours of the procedure. | 5)The patient satisfaction by Likert scale on 7th follow up day.
2) Post operative pain
时间窗: 1)The efficacy of Lornoxicam as a pre emptive analgesic. | 2)The efficacy of Lornoxicam as a post operative analgesic. | 3)Pain at 2nd, 4th, 6th, 12th, and 24th hour post operatively using VAS. | 4)The number of rescue analgesics taken within 24 hours of the procedure. | 5)The patient satisfaction by Likert scale on 7th follow up day.
3) The number of rescue analgesics taken within 24 hours of the procedure.
时间窗: 1)The efficacy of Lornoxicam as a pre emptive analgesic. | 2)The efficacy of Lornoxicam as a post operative analgesic. | 3)Pain at 2nd, 4th, 6th, 12th, and 24th hour post operatively using VAS. | 4)The number of rescue analgesics taken within 24 hours of the procedure. | 5)The patient satisfaction by Likert scale on 7th follow up day.
4) Patient satisfaction by Likert scale.
时间窗: 1)The efficacy of Lornoxicam as a pre emptive analgesic. | 2)The efficacy of Lornoxicam as a post operative analgesic. | 3)Pain at 2nd, 4th, 6th, 12th, and 24th hour post operatively using VAS. | 4)The number of rescue analgesics taken within 24 hours of the procedure. | 5)The patient satisfaction by Likert scale on 7th follow up day.
次要结局
- 1) The effectiveness of Lornoxicam as a pre emptive analgesic.(2) The effectiveness of Lornoxicam as a post operative analgesic.)
研究者
Dr Bhavana G Ammanagi
Raja Rajeswari dental college and hospital, Bangalore