Comparison the effect of distilled water and normal saline on hemodynamic parameters and ventilator associated pneumonia

Not Applicable

• Conditions: Ventilator associated pneumonia (VAP).; Ventilator associated pneumonia; J95.851

• Registration Number: IRCT20161124031068N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Negative culture of the trachea at the beginning of intubation
Systolic blood pressure more than 90 mmHg without administration of inotropic drugs
Normal level of electrolytes
Without cardiac arrhythmia
Urinary output more than 30 cc per hour
Without asthma
Without chronic obstructive pulmonary disease
Without lung infections

Exclusion Criteria

With previous asthma
With previous chronic obstructive pulmonary disease
With previous lung infections

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ventilatore associated pneumonia. Timepoint: Before intervention and 5 days after intervention. Method of measurement: Endoteracheal culture.

Secondary Outcome Measures

Name	Time	Method
Blood pressure. Timepoint: Before and 5 minutes after endotracheal suctioning. Method of measurement: Vital-signs monitoring device.;Heart rate. Timepoint: Before and 5 minutes after endotracheal suctioning. Method of measurement: Vital-signs monitoring device.;Respiratory rate. Timepoint: Before and 5 minutes after endotracheal suctioning. Method of measurement: Vital-signs monitoring device.;Peripheral blood oxygen saturation (SpO2). Timepoint: Before and 5 minutes after endotracheal suctioning. Method of measurement: pulse oximeter.