COMPARISON OF TADALAFIL AND TAMSULOSIN IN THE TREATMENT OF MALE LOWER URINARY TRACT SYMPTOMS ASSOCIATED WITH BENIGN PROSTATIC HYPERPLASIA : A RANDOMIZED, CROSSOVER STUDY
Not Applicable
Recruiting
- Conditions
- benign prostatic hyperplasia
- Registration Number
- JPRN-jRCT1051200099
- Lead Sponsor
- kimura Osamu
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 200
Inclusion Criteria
1) male patients (50 years or older, male patient younger than 90 years,and prostate volume is 20 mL or more In the sonography,and IPSS score 8 or more, and QOL score 3 or more)
2) the patients who acquired an agreement for participation of this study
Exclusion Criteria
1) the patients with prostate cancer
2) the patients with neurogenic bladder
3) the patients who was treated with other alpha1blockers or drug for overactive bladder
4) the patients who Tadalafil is administration contraindication
5) the patient who was judged to be inappropriateby by a doctor
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of change of the international prostate symptom score (IPSS) in each drug dosage start 12 weeks later
- Secondary Outcome Measures
Name Time Method The amount of change of the following item each drug dosage start 12 weeks later<br>QOL, IPSS-vas, overactivity bladder symptom score (OABSS), OABSS-vas, individual score of IPSS, NIH- Chronic Prostatitis Symptom Index (NIH-CPSI), a satisfaction questionnaire, adverse event and side effect