the effect of tamsulosin and tadalafil in response to treatment of patients with lower urinary tract symptoms
- Conditions
- Condition 1: Atherosclerosis. Condition 2: Obstructive and urinary tract symptoms.AtherosclerosisObstructive and reflux uropathy, unspecifiedN13.9
- Registration Number
- IRCT20191230045943N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 200
Male patients referred to urology clinic with obstructive and urinary tract symptoms for at least 6 months
Patients over 50 years of age
Male patients referred to urology clinic less than 50 years old
PSA higher than 10
Urine residue 300ml or higher determined by ultrasound
Receiving Finasteride during the last 3 months
Receiving anti-androgen drugs
History of pelvic surgery or radiotherapy
History of lower urinary tract malignancy
Lower urinary tract trauma
Urinary retention
Bladder stones
Urinary tract infection that is determined by urine culture
Urethral stricture
Neurological disease affecting bladder function
Secondary obstruction to the median lobe of the prostate
Prostate cancer
Liver or kidney failure
Cardiovascular diseases such as significant angina that need to be checked by a cardiologist and CHF not compensated, recent MI and uncontrolled blood pressure
treatment with nitrates
Uncontrolled diabetes HbAlc> 9%
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Treatment of obstructive and urinary tract symptoms. Timepoint: At one month intervals for three months. Method of measurement: Q max evaluation.
- Secondary Outcome Measures
Name Time Method