NCT04780607UnknownNot Applicable
Multicenter Results of Mitral Valve Surgery in Patients With Rheumatic Heart Disease
Beijing Anzhen Hospital1 site in 1 country4,000 target enrollmentStarted: January 1, 2011Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 4,000
- Locations
- 1
- Primary Endpoint
- all-cause mortality
Study Overview
Brief Summary
rheumatic heart disease remains the majority valvular disease in low and middle income countries, which mostly affected mitral valve, surgical treatment is the most effective strategy to improve the outcomes of middle or late-stage RHD patient, however, whether mitral valve repair surgery is superior to replacement or other evolving interventional device remains controversial, this study aims to investigate the results of repair surgery compared with replacement or other treatment strategy from international multicenters.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •1、rheumatic heart disease 2、mitral valve disease 3、combined with other heart valve disease(aortic valve, tricuspid valve, pulmonary valve) 4、patients underwent initial mitral valve surgery or intervention
Exclusion Criteria
- •1、congenital heart disease degenerative heart valve disease 2、isolated aortic valve or tricuspid valve, pulmonary valve disease( doesn't affect mitral valve ) 3、patients received more than 1 time mitral valve operation
Outcomes
Primary Outcomes
all-cause mortality
Time Frame: 2011-2024
death from any cause
Secondary Outcomes
No secondary outcomes reported
Investigators
Xu Meng
NO.9 department of Cardiac surgery center
Beijing Anzhen Hospital
Study Sites (1)
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